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Structure-Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy**

Drug-loaded nanoparticles (NPs) are of particular interest for efficient cancer therapy due to their improved drug delivery and therapeutic index in various types of cancer. However, the encapsulation of many chemotherapeutics into delivery NPs is often hampered by their unfavorable physicochemical...

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Detalles Bibliográficos
Autores principales:	Wang, Hangxiang, Xie, Haiyang, Wu, Jiaping, Wei, Xuyong, Zhou, Lin, Xu, Xiao, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225468/ https://www.ncbi.nlm.nih.gov/pubmed/25196427 http://dx.doi.org/10.1002/anie.201406685

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