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c-Kit Expression is Rate-Limiting for Stem Cell Factor-Mediated Disease Progression in Adenoid Cystic Carcinoma of the Salivary Glands()()

Adenoid cystic carcinoma (ACC) is an aggressive malignant neoplasm of the salivary glands in which c-Kit is overexpressed and activated, although the mechanism for this is as yet unclear. We analyzed 27 sporadic ACC tumor specimens to examine the biologic and clinical significance of c-Kit activatio...

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Detalles Bibliográficos
Autores principales: Phuchareon, Janyaporn, van Zante, Annemieke, Overdevest, Jonathan B., McCormick, Frank, Eisele, David W., Tetsu, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225653/
https://www.ncbi.nlm.nih.gov/pubmed/25389449
http://dx.doi.org/10.1016/j.tranon.2014.07.006