Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

Inhibition of the proteasome offers many therapeutic possibilities in inflammation as well as in neoplastic diseases. However, clinical use of proteasome inhibitors is limited by the development of resistance or severe side effects. In our study we characterized the anti-tumor properties of the nove...

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Detalles Bibliográficos
Autores principales: Mlynarczuk-Bialy, Izabela, Doeppner, Thorsten R., Golab, Jakub, Nowis, Dominika, Wilczynski, Grzegorz M., Parobczak, Kamil, Wigand, Moritz E., Hajdamowicz, Malgorzata, Biały, Łukasz P., Aniolek, Olga, Henklein, Petra, Bähr, Mathias, Schmidt, Boris, Kuckelkorn, Ulrike, Kloetzel, Peter-M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225687/
https://www.ncbi.nlm.nih.gov/pubmed/25389452
http://dx.doi.org/10.1016/j.tranon.2014.07.002

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