Dystrophin Is a Tumor Suppressor in Human Cancers with Myogenic Programs

Many common human mesenchymal tumors, including gastrointestinal stromal tumor (GIST), rhabdomyosarcoma (RMS), and leiomyosarcoma (LMS), feature myogenic differentiation(1–3). Here we report that intragenic deletion of the dystrophin-encoding and muscular dystrophy-associated DMD gene is a frequent...

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Detalles Bibliográficos
Autores principales: Wang, Yuexiang, Marino-Enriquez, Adrian, Bennett, Richard R., Zhu, Meijun, Shen, Yiping, Eilers, Grant, Lee, Jen-Chieh, Henze, Joern, Fletcher, Benjamin S., Gu, Zhizhan, Fox, Edward A., Antonescu, Cristina R., Fletcher, Christopher D.M., Guo, Xiangqian, Raut, Chandrajit P., Demetri, George D., van de Rijn, Matt, Ordog, Tamas, Kunkel, Louis M., Fletcher, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225780/
https://www.ncbi.nlm.nih.gov/pubmed/24793134
http://dx.doi.org/10.1038/ng.2974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225780/
https://www.ncbi.nlm.nih.gov/pubmed/24793134
http://dx.doi.org/10.1038/ng.2974

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