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Amyloid Beta(1–42) and the Phoshorylated Tau Threonine 231 in Brains of Aged Cynomolgus Monkeys (Macaca fascicularis)
Pathological hallmarks indicative of Alzheimer’s disease (AD), which are the plaques of amyloid beta(1–42) and neurofibrillary tangles, were found in brain of aged cynomolgus monkey. The aim of this study was to investigate if aged monkeys exhibiting spatial memory impairment and levels of biomarker...
Autores principales: | Darusman, Huda Shalahudin, Gjedde, Albert, Sajuthi, Dondin, Schapiro, Steven J., Kalliokoski, Otto, Kristianingrum, Yuli P., Handaryani, Ekowati, Hau, Jann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225838/ https://www.ncbi.nlm.nih.gov/pubmed/25426069 http://dx.doi.org/10.3389/fnagi.2014.00313 |
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