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Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice

BACKGROUND: Vpu is a multifunctional accessory protein that enhances the release of HIV-1 by counteracting the entrapment of nascent virions on infected cell surface mediated by BST2/Tetherin. Vpu-mediated BST2 antagonism involves physical association with BST2 and subsequent mislocalization of the...

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Detalles Bibliográficos
Autores principales:	Dave, Vibhuti P, Hajjar, Fadi, Dieng, Mame Massar, Haddad, Élie, Cohen, Éric A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226203/ https://www.ncbi.nlm.nih.gov/pubmed/24195843 http://dx.doi.org/10.1186/1742-4690-10-128

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