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Connection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA Repair

Genomic instability finally induces cell death or apoptosis. The tumor suppressor, phosphatase and tensin homolog on chromosome 10 (PTEN), is a dual-specificity phosphatase, which has protein phosphatase activity and lipid phosphatase activity that antagonizes PI3K activity. Cells that lack PTEN hav...

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Detalles Bibliográficos
Autores principales:	Minami, Akari, Nakanishi, Atsuko, Ogura, Yasunori, Kitagishi, Yasuko, Matsuda, Satoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226230/ https://www.ncbi.nlm.nih.gov/pubmed/25426449 http://dx.doi.org/10.3389/fonc.2014.00318

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