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Association Studies with Imputed Variants Using Expectation-Maximization Likelihood-Ratio Tests

Genotype imputation has become standard practice in modern genetic studies. As sequencing-based reference panels continue to grow, increasingly more markers are being well or better imputed but at the same time, even more markers with relatively low minor allele frequency are being imputed with low...

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Detalles Bibliográficos
Autores principales: Huang, Kuan-Chieh, Sun, Wei, Wu, Ying, Chen, Mengjie, Mohlke, Karen L., Lange, Leslie A., Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226494/
https://www.ncbi.nlm.nih.gov/pubmed/25383782
http://dx.doi.org/10.1371/journal.pone.0110679