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Association Studies with Imputed Variants Using Expectation-Maximization Likelihood-Ratio Tests
Genotype imputation has become standard practice in modern genetic studies. As sequencing-based reference panels continue to grow, increasingly more markers are being well or better imputed but at the same time, even more markers with relatively low minor allele frequency are being imputed with low...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226494/ https://www.ncbi.nlm.nih.gov/pubmed/25383782 http://dx.doi.org/10.1371/journal.pone.0110679 |