Peroxisome Proliferator-Activated Receptor γ Deficiency in T Cells Accelerates Chronic Rejection by Influencing the Differentiation of CD4+ T Cells and Alternatively Activated Macrophages

BACKGROUND: In a previous study, activation of the peroxisome proliferator–activated receptor γ (PPARγ) inhibited chronic cardiac rejection. However, because of the complexity of chronic rejection and the fact that PPARγ is widely expressed in immune cells, the mechanism of the PPARγ - induced prote...

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Detalles Bibliográficos
Autores principales: Huang, Xiaofan, Ren, Lingyun, Ye, Ping, Cheng, Chao, Wu, Jie, Wang, Sihua, Sun, Yuan, Liu, Zheng, Xie, Aini, Xia, Jiahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226585/
https://www.ncbi.nlm.nih.gov/pubmed/25383620
http://dx.doi.org/10.1371/journal.pone.0112953

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