Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

Classifying adult gliomas remains largely a histologic diagnosis based on morphology; however astrocytic, oligodendroglial and mixed lineage tumors can display overlapping histologic features. We used multiplexed exome sequencing (OncoPanel) on 108 primary or recurrent adult gliomas, comprising 65 o...

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Detalles Bibliográficos
Autores principales: Cryan, Jane B., Haidar, Sam, Ramkissoon, Lori A., Bi, Wenya Linda, Knoff, David S., Schultz, Nikolaus, Abedalthagafi, Malak, Brown, Loreal, Wen, Patrick Y., Reardon, David A., Dunn, Ian F., Folkerth, Rebecca D., Santagata, Sandro, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Hornick, Jason L., Alexander, Brian M., Ligon, Keith L., Ramkissoon, Shakti H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226668/
https://www.ncbi.nlm.nih.gov/pubmed/25257301

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