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Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells

Imatinib Mesylate (IM) and other tyrosine kinase inhibitor (TKI) therapies have had a major impact on the treatment of chronic myeloid leukemia (CML). However, TKI monotherapy is not curative, with relapse and persistence of leukemic stem cells (LSCs) remaining a challenge. We have recently identifi...

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Detalles Bibliográficos
Autores principales:	Lin, Hanyang, Chen, Min, Rothe, Katharina, Lorenzi, Matthew V., Woolfson, Adrian, Jiang, Xiaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226710/ https://www.ncbi.nlm.nih.gov/pubmed/25226617

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