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Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 Å resolution shows the closed structure of the substrate-binding cleft

Peptidyl-tRNA hydrolase (Pth) catalyses the release of tRNA and peptide components from peptidyl-tRNA molecules. Pth from a Gram-positive bacterium Streptococcus pyogenes (SpPth) was cloned, expressed, purified and crystallised. Three-dimensional structure of SpPth was determined by X-ray crystallog...

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Detalles Bibliográficos
Autores principales:	Singh, Avinash, Gautam, Lovely, Sinha, Mau, Bhushan, Asha, Kaur, Punit, Sharma, Sujata, Singh, T.P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226762/ https://www.ncbi.nlm.nih.gov/pubmed/25389518 http://dx.doi.org/10.1016/j.fob.2014.10.010

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