Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study

BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We r...

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Detalles Bibliográficos
Autores principales: De Cecio, Rossella, Cantile, Monica, Collina, Francesca, Marra, Laura, Santonastaso, Clemente, Scaffa, Cono, Botti, Gerardo, Losito, Nunzia Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226905/
https://www.ncbi.nlm.nih.gov/pubmed/25358264
http://dx.doi.org/10.1186/s13048-014-0101-7
Descripción
Sumario:BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13048-014-0101-7) contains supplementary material, which is available to authorized users.

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