Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study

BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We r...

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Autores principales: De Cecio, Rossella, Cantile, Monica, Collina, Francesca, Marra, Laura, Santonastaso, Clemente, Scaffa, Cono, Botti, Gerardo, Losito, Nunzia Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226905/
https://www.ncbi.nlm.nih.gov/pubmed/25358264
http://dx.doi.org/10.1186/s13048-014-0101-7
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author De Cecio, Rossella
Cantile, Monica
Collina, Francesca
Marra, Laura
Santonastaso, Clemente
Scaffa, Cono
Botti, Gerardo
Losito, Nunzia Simona
author_facet De Cecio, Rossella
Cantile, Monica
Collina, Francesca
Marra, Laura
Santonastaso, Clemente
Scaffa, Cono
Botti, Gerardo
Losito, Nunzia Simona
author_sort De Cecio, Rossella
collection PubMed
description BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13048-014-0101-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-42269052014-11-12 Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study De Cecio, Rossella Cantile, Monica Collina, Francesca Marra, Laura Santonastaso, Clemente Scaffa, Cono Botti, Gerardo Losito, Nunzia Simona J Ovarian Res Case Report BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13048-014-0101-7) contains supplementary material, which is available to authorized users. BioMed Central 2014-10-29 /pmc/articles/PMC4226905/ /pubmed/25358264 http://dx.doi.org/10.1186/s13048-014-0101-7 Text en © De Cecio et al.; licensee BioMed Central Ltd. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
De Cecio, Rossella
Cantile, Monica
Collina, Francesca
Marra, Laura
Santonastaso, Clemente
Scaffa, Cono
Botti, Gerardo
Losito, Nunzia Simona
Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title_full Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title_fullStr Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title_full_unstemmed Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title_short Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study
title_sort borderline brenner tumor of the ovary: a case report with immunohistochemical and molecular study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226905/
https://www.ncbi.nlm.nih.gov/pubmed/25358264
http://dx.doi.org/10.1186/s13048-014-0101-7
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