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A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam

BACKGROUND: Close contacts of tuberculosis (TB) patients are at increased risk of developing tuberculosis. Although passive contact screening guidelines are incorporated in the national TB control program, currently it is unknown how frequent close contacts are screened for TB in Vietnam. This study...

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Autores principales: Thanh, Thuy Hoang Thi, Ngoc, Sy Dinh, Viet, Nhung Nguyen, Van, Hung Nguyen, Horby, Peter, Cobelens, Frank GJ, Wertheim, Heiman FL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226947/
https://www.ncbi.nlm.nih.gov/pubmed/25015682
http://dx.doi.org/10.1186/1471-2458-14-713
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author Thanh, Thuy Hoang Thi
Ngoc, Sy Dinh
Viet, Nhung Nguyen
Van, Hung Nguyen
Horby, Peter
Cobelens, Frank GJ
Wertheim, Heiman FL
author_facet Thanh, Thuy Hoang Thi
Ngoc, Sy Dinh
Viet, Nhung Nguyen
Van, Hung Nguyen
Horby, Peter
Cobelens, Frank GJ
Wertheim, Heiman FL
author_sort Thanh, Thuy Hoang Thi
collection PubMed
description BACKGROUND: Close contacts of tuberculosis (TB) patients are at increased risk of developing tuberculosis. Although passive contact screening guidelines are incorporated in the national TB control program, currently it is unknown how frequent close contacts are screened for TB in Vietnam. This study assesses current contact screening practices in Vietnam and determines the proportion of household contacts screened of newly registered TB patients. METHOD: Survey of household contacts of smear-positive TB patients (index patients) registered for treatment in 2008 in three Vietnamese cities. Households were interviewed in 2010 about screening for TB since treatment registration date of the index patient. RESULTS: We interviewed 4,118 household contacts of 1,091 identified index cases. Contact screening mainly relied on self-referral by household contacts. Of the 4,118 household contacts, 474 (11.5%) self-referred for TB screening, while this screening proportion was only 5.5% among contacts under 5 years old (16/293). Sputum examinations were performed in 374 (78.9%) of the screened contacts. Contact screening identified 27 cases of pulmonary TB (0.7%; or 656 cases/100,000 contacts), of which 20 were detected by sputum smear. CONCLUSIONS: The low proportion of household TB contacts screened for TB illustrates the limitations of passive contact screening as currently practiced in Vietnam. Children under 5 years of age are particularly neglected with this approach. Active contact screening with fixed follow-up times of close contacts of newly diagnosed TB patients should be considered in Vietnam, particularly in case of young children and drug-resistant TB.
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spelling pubmed-42269472014-11-12 A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam Thanh, Thuy Hoang Thi Ngoc, Sy Dinh Viet, Nhung Nguyen Van, Hung Nguyen Horby, Peter Cobelens, Frank GJ Wertheim, Heiman FL BMC Public Health Research Article BACKGROUND: Close contacts of tuberculosis (TB) patients are at increased risk of developing tuberculosis. Although passive contact screening guidelines are incorporated in the national TB control program, currently it is unknown how frequent close contacts are screened for TB in Vietnam. This study assesses current contact screening practices in Vietnam and determines the proportion of household contacts screened of newly registered TB patients. METHOD: Survey of household contacts of smear-positive TB patients (index patients) registered for treatment in 2008 in three Vietnamese cities. Households were interviewed in 2010 about screening for TB since treatment registration date of the index patient. RESULTS: We interviewed 4,118 household contacts of 1,091 identified index cases. Contact screening mainly relied on self-referral by household contacts. Of the 4,118 household contacts, 474 (11.5%) self-referred for TB screening, while this screening proportion was only 5.5% among contacts under 5 years old (16/293). Sputum examinations were performed in 374 (78.9%) of the screened contacts. Contact screening identified 27 cases of pulmonary TB (0.7%; or 656 cases/100,000 contacts), of which 20 were detected by sputum smear. CONCLUSIONS: The low proportion of household TB contacts screened for TB illustrates the limitations of passive contact screening as currently practiced in Vietnam. Children under 5 years of age are particularly neglected with this approach. Active contact screening with fixed follow-up times of close contacts of newly diagnosed TB patients should be considered in Vietnam, particularly in case of young children and drug-resistant TB. BioMed Central 2014-07-11 /pmc/articles/PMC4226947/ /pubmed/25015682 http://dx.doi.org/10.1186/1471-2458-14-713 Text en Copyright © 2014 Thanh et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Thanh, Thuy Hoang Thi
Ngoc, Sy Dinh
Viet, Nhung Nguyen
Van, Hung Nguyen
Horby, Peter
Cobelens, Frank GJ
Wertheim, Heiman FL
A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title_full A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title_fullStr A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title_full_unstemmed A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title_short A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam
title_sort household survey on screening practices of household contacts of smear positive tuberculosis patients in vietnam
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226947/
https://www.ncbi.nlm.nih.gov/pubmed/25015682
http://dx.doi.org/10.1186/1471-2458-14-713
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