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Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome

BACKGROUND: Hypervariable region 1 (HVR1) contained within envelope protein 2 (E2) gene is the most variable part of HCV genome and its translation product is a major target for the host immune response. Variability within HVR1 may facilitate evasion of the immune response and could affect treatment...

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Detalles Bibliográficos
Autores principales:	Caraballo Cortés, Kamila, Zagordi, Osvaldo, Perlejewski, Karol, Laskus, Tomasz, Maroszek, Krzysztof, Bukowska-Ośko, Iwona, Pawełczyk, Agnieszka, Płoski, Rafał, Berak, Hanna, Horban, Andrzej, Radkowski, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226954/ https://www.ncbi.nlm.nih.gov/pubmed/25016390 http://dx.doi.org/10.1186/1471-2334-14-389

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