Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain

BACKGROUND: Opioids have been used for the management of pain and coadministration of two opioids may induce synergism. In a model of tonic pain, the acetic acid writhing test and in a phasic model, the hot plate, the antinociceptive interaction between fentanyl, methadone, morphine, and tramadol wa...

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Detalles Bibliográficos
Autores principales: Miranda, Hugo F, Noriega, Viviana, Zanetta, Pilar, Prieto, Juan Carlos, Prieto-Rayo, Juan Carlos, Aranda, Nicolás, Sierralta, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226961/
https://www.ncbi.nlm.nih.gov/pubmed/25017386
http://dx.doi.org/10.1186/s12929-014-0062-6

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