Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

INTRODUCTION: Peroxiredoxin-1 (PRDX1) is a multifunctional protein, acting as a hydrogen peroxide (H(2)O(2)) scavenger, molecular chaperone and immune modulator. Although differential PRDX1 expression has been described in many tumors, the potential role of PRDX1 in breast cancer remains highly ambi...

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Detalles Bibliográficos
Autores principales: O’Leary, Patrick C, Terrile, Marta, Bajor, Malgorzata, Gaj, Pawel, Hennessy, Bryan T, Mills, Gordon B, Zagozdzon, Agnieszka, O’Connor, Darran P, Brennan, Donal J, Connor, Kate, Li, Jane, Gonzalez-Angulo, Ana Maria, Sun, Han-Dong, Pu, Jian-Xin, Pontén, Fredrik, Uhlén, Mathias, Jirström, Karin, Nowis, Dominika A, Crown, John P, Zagozdzon, Radoslaw, Gallagher, William M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226972/
https://www.ncbi.nlm.nih.gov/pubmed/25011585
http://dx.doi.org/10.1186/bcr3691

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