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Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice
INTRODUCTION: Syndecans are heparan sulphate proteoglycans expressed by endothelial cells. Syndecan-3 is expressed by synovial endothelial cells of rheumatoid arthritis (RA) patients where it binds chemokines, suggesting a role in leukocyte trafficking. The objective of the current study was to exam...
Autores principales: | Kehoe, Oksana, Kalia, Neena, King, Sophie, Eustace, Andrew, Boyes, Charlotte, Reizes, Ofer, Williams, Anwen, Patterson, Angela, Middleton, Jim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227035/ https://www.ncbi.nlm.nih.gov/pubmed/25015005 http://dx.doi.org/10.1186/ar4610 |
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