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Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis

In amyotrophic lateral sclerosis (ALS) the large motoneurons that innervate the fast-contracting muscle fibers (F-type motoneurons) are vulnerable and degenerate in adulthood. In contrast, the small motoneurons that innervate the slow-contracting fibers (S-type motoneurons) are resistant and do not...

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Detalles Bibliográficos
Autores principales:	Leroy, Félix, Lamotte d'Incamps, Boris, Imhoff-Manuel, Rebecca D, Zytnicki, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227046/ https://www.ncbi.nlm.nih.gov/pubmed/25313866 http://dx.doi.org/10.7554/eLife.04046

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