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Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo

INTRODUCTION: The cancer stem cell model implies a hierarchical organization within breast tumors maintained by cancer stem-like cells (CSCs). Accordingly, CSCs are a subpopulation of cancer cells with capacity for self-renewal, differentiation and tumor initiation. These cells can be isolated throu...

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Detalles Bibliográficos
Autores principales: Klevebring, Daniel, Rosin, Gustaf, Ma, Ran, Lindberg, Johan, Czene, Kamila, Kere, Juha, Fredriksson, Irma, Bergh, Jonas, Hartman, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227057/
https://www.ncbi.nlm.nih.gov/pubmed/24998755
http://dx.doi.org/10.1186/bcr3687