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Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo
INTRODUCTION: The cancer stem cell model implies a hierarchical organization within breast tumors maintained by cancer stem-like cells (CSCs). Accordingly, CSCs are a subpopulation of cancer cells with capacity for self-renewal, differentiation and tumor initiation. These cells can be isolated throu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227057/ https://www.ncbi.nlm.nih.gov/pubmed/24998755 http://dx.doi.org/10.1186/bcr3687 |