Cargando…

Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients

INTRODUCTION: Purified prothrombin complex concentrate (PCC) is increasingly used as hemostatic therapy for trauma-induced coagulopathy (TIC). However, the impact of PCC administration on coagulation status among patients with TIC has not been adequately investigated. METHODS: In this observational,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schöchl, Herbert, Voelckel, Wolfgang, Maegele, Marc, Kirchmair, Lukas, Schlimp, Christoph J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227066/ https://www.ncbi.nlm.nih.gov/pubmed/25008277 http://dx.doi.org/10.1186/cc13982

Ejemplares similares

Impact of fibrinogen concentrate alone or with prothrombin complex concentrate (+/− fresh frozen plasma) on plasma fibrinogen level and fibrin-based clot strength (FIBTEM) in major trauma: a retrospective study
por: Schlimp, Christoph J, et al.
Publicado: (2013)

Fibrinogen levels in trauma patients during the first seven days after fibrinogen concentrate therapy: a retrospective study
por: Schlimp, Christoph J., et al.
Publicado: (2016)

Effect of coagulation factor concentrate administration on ROTEM® parameters in major trauma
por: Ponschab, Martin, et al.
Publicado: (2015)

Estimation of plasma fibrinogen levels based on hemoglobin, base excess and Injury Severity Score upon emergency room admission
por: Schlimp, Christoph J, et al.
Publicado: (2013)

Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM(®))-guided administration of fibrinogen concentrate and prothrombin complex concentrate
por: Schöchl, Herbert, et al.
Publicado: (2010)

Impact of Idarucizumab and Andexanet Alfa on DOAC Plasma Concentration and ClotPro(®) Clotting Time: An Ex Vivo Spiking Study in A Cohort of Trauma Patients
por: Oberladstätter, Daniel, et al.
Publicado: (2021)

Early and individualized goal-directed therapy for trauma-induced coagulopathy
por: Schöchl, Herbert, et al.
Publicado: (2012)

Multiplate Platelet Function Testing upon Emergency Room Admission Fails to Provide Useful Information in Major Trauma Patients Not on Platelet Inhibitors
por: Pommer, Peter, et al.
Publicado: (2022)

Sufficient Thrombin Generation Despite 95% Hemodilution: An In Vitro Experimental Study
por: Gratz, Johannes, et al.
Publicado: (2020)

Operability of a Resonance-Based Viscoelastic Haemostatic Analyzer in the High-Vibration Environment of Air Medical Transport
por: Zipperle, Johannes, et al.
Publicado: (2022)

Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
por: Schöchl, Herbert, et al.
Publicado: (2011)

High Interleukin-6 Plasma Concentration upon Admission Is Predictive of Massive Transfusion in Severely Injured Patients
por: Weichselbaum, Nadja, et al.
Publicado: (2021)

Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model
por: Grottke, Oliver, et al.
Publicado: (2013)

Conventional and Pro-Inflammatory Pathways of Fibrinolytic Activation in Non-Traumatic Hyperfibrinolysis
por: Zipperle, Johannes, et al.
Publicado: (2022)

The impact of direct oral anticoagulants in traumatic brain injury patients greater than 60-years-old
por: Prexl, Oliver, et al.
Publicado: (2018)

Theoretical Modeling of Coagulation Management With Therapeutic Plasma or Prothrombin Complex Concentrate
por: Schöchl, Herbert, et al.
Publicado: (2017)

Postponing intubation in spontaneously breathing major trauma patients upon emergency room admission does not impair outcome
por: Schwaiger, Philipp, et al.
Publicado: (2019)

FIBTEM provides early prediction of massive transfusion in trauma
por: Schöchl, Herbert, et al.
Publicado: (2011)

Factor XIII Measurement and Substitution in Trauma Patients after Admission to an Intensive Care Unit
por: Katzensteiner, Moritz, et al.
Publicado: (2022)

Recovery of fibrinogen concentrate after intraosseous application is equivalent to the intravenous route in a porcine model of hemodilution
por: Schlimp, Christoph J., et al.
Publicado: (2014)

Effectiveness of prothrombin complex concentrate for the treatment of bleeding: A systematic review and meta‐analysis
por: van den Brink, Daan P., et al.
Publicado: (2020)

Characterization of thrombin derived from human recombinant prothrombin
por: Lövgren, Ann, et al.
Publicado: (2015)

Impaired platelet‐dependent thrombin generation associated with thrombocytopenia is improved by prothrombin complex concentrates in vitro
por: Chowdary, Pratima, et al.
Publicado: (2020)

Role of prothrombin complex concentrate in the severe trauma patient
por: Egea-Guerrero, Juan José, et al.
Publicado: (2022)

Computer tomographic assessment of gastric volume in major trauma patients: impact of pre-hospital airway management on gastric air
por: Mitteregger, Thomas, et al.
Publicado: (2020)

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis
por: Kremers, Romy M. W., et al.
Publicado: (2017)

3-Factor versus 4-Factor Prothrombin Complex Concentrates for the Reversal of Vitamin K Antagonist-Associated Coagulopathy: A Systematic Review and Meta-analysis
por: Puchstein, Dorothea, et al.
Publicado: (2023)

Efficacy of prehospital administration of fibrinogen concentrate in trauma patients bleeding or presumed to bleed (FIinTIC): A multicentre, double-blind, placebo-controlled, randomised pilot study
por: Ziegler, Bernhard, et al.
Publicado: (2021)

Comparison of prothrombin complex concentrate and fresh frozen plasma on thrombin generation and hemorrhage in experimental dilutional coagulopathy
por: Dickneite, G, et al.
Publicado: (2008)

Andexanet versus prothrombin complex concentrates: Differences in reversal of factor Xa inhibitors in in vitro thrombin generation
por: Lu, Genmin, et al.
Publicado: (2020)

Rapid measurement of fibrinogen concentration in whole blood using a steel ball coagulometer
por: Schlimp, Christoph J., et al.
Publicado: (2015)

Using of prothrombin complex concentrate in patients with trauma-induced coagulopathy
por: Tarabrin, O, et al.
Publicado: (2015)

Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial
por: Schenk, Bettina, et al.
Publicado: (2018)

Clinical use of topical thrombin as a surgical hemostat
por: Lew, Wesley K, et al.
Publicado: (2008)

Reversal of rivaroxaban anticoagulant effect by prothrombin complex concentrates: which dose is sufficient to restore normal thrombin generation?
por: Giffard-Quillon, Lorine, et al.
Publicado: (2020)

Reversing direct factor Xa or thrombin inhibitors: Factor V addition to prothrombin complex concentrate is beneficial in vitro
por: Brinkman, Herm Jan M., et al.
Publicado: (2022)

STUDIES ON BLOOD COAGULATION : I. THE RÔLE OF PROTHROMBIN AND OF PLATELETS IN THE FORMATION OF THROMBIN
por: Eagle, Harry
Publicado: (1935)

Variations and obstacles in the use of coagulation factor concentrates for major trauma bleeding across Europe: outcomes from a European expert meeting
por: Černý, Vladimir, et al.
Publicado: (2021)

Comparison of fibrin-based clot elasticity parameters measured by free oscillation rheometry (ReoRox(®)) versus thromboelastometry (ROTEM(®))
por: Solomon, Cristina, et al.
Publicado: (2015)

Assessing the Methodology for Calculating Platelet Contribution to Clot Strength (Platelet Component) in Thromboelastometry and Thrombelastography
por: Solomon, Cristina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_alnncnm1ipnmtqclp9jcgrq3u5