Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants

BACKGROUND: Following transmission, HIV-1 evolves into a diverse population, and next generation sequencing enables us to detect variants occurring at low frequencies. Studying viral evolution at the level of whole genomes was hitherto not possible because next generation sequencing delivers relativ...

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Detalles Bibliográficos
Autores principales: Pandit, Aridaman, de Boer, Rob J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227095/
https://www.ncbi.nlm.nih.gov/pubmed/24996694
http://dx.doi.org/10.1186/1742-4690-11-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227095/
https://www.ncbi.nlm.nih.gov/pubmed/24996694
http://dx.doi.org/10.1186/1742-4690-11-56

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