Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas

BACKGROUND: Grade IV glioblastomas exist in two forms, primary (de novo) glioblastomas (pGBM) that arise without precursor lesions, and the less common secondary glioblastomas (sGBM) which develop from earlier lower grade lesions. Genetic heterogeneity between pGBM and sGBM has been documented as ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Hill, Victoria K, Shinawi, Thoraia, Ricketts, Christopher J, Krex, Dietmar, Schackert, Gabriele, Bauer, Julien, Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227105/
https://www.ncbi.nlm.nih.gov/pubmed/25012071
http://dx.doi.org/10.1186/1471-2407-14-506

Ejemplares similares

Ejemplares similares