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Prolonged continuous intravenous infusion of the dipeptide L-alanine- L-glutamine significantly increases plasma glutamine and alanine without elevating brain glutamate in patients with severe traumatic brain injury

INTRODUCTION: Low plasma glutamine levels are associated with worse clinical outcome. Intravenous glutamine infusion dose- dependently increases plasma glutamine levels, thereby correcting hypoglutaminemia. Glutamine may be transformed to glutamate which might limit its application at a higher dose...

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Detalles Bibliográficos
Autores principales: Nägeli, Mirjam, Fasshauer, Mario, Sommerfeld, Jutta, Fendel, Angela, Brandi, Giovanna, Stover, John F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227121/
https://www.ncbi.nlm.nih.gov/pubmed/24992948
http://dx.doi.org/10.1186/cc13962