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Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester–induced apoptosis in C6 glioma cells

BACKGROUND: Caffeic acid phenethyl ester (CAPE), a component of propolis, is reported to possess anti-inflammatory, anti-bacterial, anti-viral, and anti-tumor activities. Previously, our laboratory demonstrated the in vitro and in vivo bioactivity of CAPE and addressed the role of p53 and the p38 mi...

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Detalles Bibliográficos
Autores principales: Tseng, Tsui-Hwa, Shen, Chien-Heng, Huang, Wen-Shih, Chen, Cheng-Nan, Liang, Wen-Hai, Lin, Tseng-Hsi, Kuo, Hsing-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227122/
https://www.ncbi.nlm.nih.gov/pubmed/24997497
http://dx.doi.org/10.1186/1423-0127-21-61