Inhibition of hematopoietic prostaglandin D(2) Synthase (H-PGDS) by an alkaloid extract from Combretum molle

BACKGROUND: Hematopoietic prostaglandin D(2) synthase (H-PGDS, GST Sigma) is a member of the glutathione S-transferase super family of enzymes that catalyses the conjugation of electrophilic substances with reduced glutathione. The enzyme catalyses the conversion of PGH(2) to PGD(2) which mediates i...

Descripción completa

Detalles Bibliográficos
Autores principales: Moyo, Rejoice, Chimponda, Theresa, Mukanganyama, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227128/
https://www.ncbi.nlm.nih.gov/pubmed/24996417
http://dx.doi.org/10.1186/1472-6882-14-221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227128/
https://www.ncbi.nlm.nih.gov/pubmed/24996417
http://dx.doi.org/10.1186/1472-6882-14-221

Ejemplares similares