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Inhibition of hematopoietic prostaglandin D(2) Synthase (H-PGDS) by an alkaloid extract from Combretum molle

BACKGROUND: Hematopoietic prostaglandin D(2) synthase (H-PGDS, GST Sigma) is a member of the glutathione S-transferase super family of enzymes that catalyses the conjugation of electrophilic substances with reduced glutathione. The enzyme catalyses the conversion of PGH(2) to PGD(2) which mediates i...

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Detalles Bibliográficos
Autores principales:	Moyo, Rejoice, Chimponda, Theresa, Mukanganyama, Stanley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227128/ https://www.ncbi.nlm.nih.gov/pubmed/24996417 http://dx.doi.org/10.1186/1472-6882-14-221

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