Modulation of chemokine gradients by apheresis redirects leukocyte trafficking to different compartments during sepsis, studies in a rat model

INTRODUCTION: Prior work suggests that leukocyte trafficking is determined by local chemokine gradients between the nidus of infection and the plasma. We recently demonstrated that therapeutic apheresis can alter immune mediator concentrations in the plasma, protect against organ injury, and improve...

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Detalles Bibliográficos
Autores principales: Peng, Zhi-Yong, Bishop, Jeffery V, Wen, Xiao-Yan, Elder, Michele M, Zhou, Feihu, Chuasuwan, Anan, Carter, Melinda J, Devlin, Jason E, Kaynar, A Murat, Singbartl, Kai, Pike, Francis, Parker, Robert S, Clermont, Gilles, Federspiel, William J, Kellum, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227131/
https://www.ncbi.nlm.nih.gov/pubmed/24992991
http://dx.doi.org/10.1186/cc13969

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