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A Functional Polymorphism in the 3'-UTR of PXR Interacts with Smoking to Increase Lung Cancer Risk in Southern and Eastern Chinese Smoker

Pregnane X receptor (PXR) is an important member of the nuclear receptor superfamily that copes with various endobiotic and xenobiotic stimuli, such as carcinogens by regulating an array of environmental response genes. Low PXR expression has been shown to promote tumor initiation and metastasis. Th...

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Detalles Bibliográficos
Autores principales:	Zhang, Lisha, Qiu, Fuman, Lu, Xiaoxiao, Li, Yinyan, Fang, Wenxiang, Zhang, Lan, Zhou, Yifeng, Yang, Lei, Lu, Jiachun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227172/ https://www.ncbi.nlm.nih.gov/pubmed/25268617 http://dx.doi.org/10.3390/ijms151017457

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