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Discovery and in Vivo Evaluation of Novel RGD-Modified Lipid-Polymer Hybrid Nanoparticles for Targeted Drug Delivery
In the current study, the lipid-shell and polymer-core hybrid nanoparticles (lpNPs) modified by Arg–Gly–Asp(RGD) peptide, loaded with curcumin (Cur), were developed by emulsification-solvent volatilization method. The RGD-modified hybrid nanoparticles (RGD–lpNPs) could overcome the poor water solubi...
Autores principales: | Zhao, Yinbo, Lin, Dayong, Wu, Fengbo, Guo, Li, He, Gu, Ouyang, Liang, Song, Xiangrong, Huang, Wei, Li, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227178/ https://www.ncbi.nlm.nih.gov/pubmed/25268623 http://dx.doi.org/10.3390/ijms151017565 |
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