Platelets: Still a Therapeutical Target for Haemostatic Disorders

Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new bi...

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Detalles Bibliográficos
Autores principales: Geraldo, Reinaldo Barros, Sathler, Plínio Cunha, Lourenço, André Luiz, Saito, Max Seidy, Cabral, Lucio M., Rampelotto, Pabulo Henrique, Castro, Helena Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227196/
https://www.ncbi.nlm.nih.gov/pubmed/25295482
http://dx.doi.org/10.3390/ijms151017901
Descripción
Sumario:Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored.

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