Platelets: Still a Therapeutical Target for Haemostatic Disorders

Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new bi...

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Autores principales: Geraldo, Reinaldo Barros, Sathler, Plínio Cunha, Lourenço, André Luiz, Saito, Max Seidy, Cabral, Lucio M., Rampelotto, Pabulo Henrique, Castro, Helena Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227196/
https://www.ncbi.nlm.nih.gov/pubmed/25295482
http://dx.doi.org/10.3390/ijms151017901
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author Geraldo, Reinaldo Barros
Sathler, Plínio Cunha
Lourenço, André Luiz
Saito, Max Seidy
Cabral, Lucio M.
Rampelotto, Pabulo Henrique
Castro, Helena Carla
author_facet Geraldo, Reinaldo Barros
Sathler, Plínio Cunha
Lourenço, André Luiz
Saito, Max Seidy
Cabral, Lucio M.
Rampelotto, Pabulo Henrique
Castro, Helena Carla
author_sort Geraldo, Reinaldo Barros
collection PubMed
description Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored.
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spelling pubmed-42271962014-11-12 Platelets: Still a Therapeutical Target for Haemostatic Disorders Geraldo, Reinaldo Barros Sathler, Plínio Cunha Lourenço, André Luiz Saito, Max Seidy Cabral, Lucio M. Rampelotto, Pabulo Henrique Castro, Helena Carla Int J Mol Sci Review Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored. MDPI 2014-10-07 /pmc/articles/PMC4227196/ /pubmed/25295482 http://dx.doi.org/10.3390/ijms151017901 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Geraldo, Reinaldo Barros
Sathler, Plínio Cunha
Lourenço, André Luiz
Saito, Max Seidy
Cabral, Lucio M.
Rampelotto, Pabulo Henrique
Castro, Helena Carla
Platelets: Still a Therapeutical Target for Haemostatic Disorders
title Platelets: Still a Therapeutical Target for Haemostatic Disorders
title_full Platelets: Still a Therapeutical Target for Haemostatic Disorders
title_fullStr Platelets: Still a Therapeutical Target for Haemostatic Disorders
title_full_unstemmed Platelets: Still a Therapeutical Target for Haemostatic Disorders
title_short Platelets: Still a Therapeutical Target for Haemostatic Disorders
title_sort platelets: still a therapeutical target for haemostatic disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227196/
https://www.ncbi.nlm.nih.gov/pubmed/25295482
http://dx.doi.org/10.3390/ijms151017901
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