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Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

The tumor necrosis factor (TNF)-related apoptosis-inducing ligand- receptor (TRAIL-R) family has emerged as a key mediator of cell fate and survival. Ligation of TRAIL ligand to TRAIL-R1 or TRAIL-R2 initiates the extrinsic apoptotic pathway characterized by the recruitment of death domains, assembly...

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Detalles Bibliográficos
Autores principales: Sarhan, Dhifaf, D’Arcy, Padraig, Lundqvist, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227232/
https://www.ncbi.nlm.nih.gov/pubmed/25318057
http://dx.doi.org/10.3390/ijms151018557