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CYP24A1 Expression Inversely Correlates with Melanoma Progression: Clinic-Pathological Studies
The major role of 24-hydroxylase (CYP24A1) is to maintain 1,25-dihydroxyvitamin D3 (1,25(OH)(2)D3) homeostasis. Recently, it has been discovered that CYP24A1 also catalyses the hydroxylation of 20(OH)D3, producing dihydroxy-derivatives that show very effective antitumorigenic activities. Previously...
Autores principales: | Brożyna, Anna A., Jochymski, Cezary, Janjetovic, Zorica, Jóźwicki, Wojciech, Tuckey, Robert C., Slominski, Andrzej T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227257/ https://www.ncbi.nlm.nih.gov/pubmed/25334067 http://dx.doi.org/10.3390/ijms151019000 |
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