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Stem Cell Treatment for Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227270/ https://www.ncbi.nlm.nih.gov/pubmed/25342318 http://dx.doi.org/10.3390/ijms151019226 |
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author | Li, Ming Guo, Kequan Ikehara, Susumu |
author_facet | Li, Ming Guo, Kequan Ikehara, Susumu |
author_sort | Li, Ming |
collection | PubMed |
description | Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD. |
format | Online Article Text |
id | pubmed-4227270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-42272702014-11-12 Stem Cell Treatment for Alzheimer’s Disease Li, Ming Guo, Kequan Ikehara, Susumu Int J Mol Sci Review Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD. MDPI 2014-10-23 /pmc/articles/PMC4227270/ /pubmed/25342318 http://dx.doi.org/10.3390/ijms151019226 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Li, Ming Guo, Kequan Ikehara, Susumu Stem Cell Treatment for Alzheimer’s Disease |
title | Stem Cell Treatment for Alzheimer’s Disease |
title_full | Stem Cell Treatment for Alzheimer’s Disease |
title_fullStr | Stem Cell Treatment for Alzheimer’s Disease |
title_full_unstemmed | Stem Cell Treatment for Alzheimer’s Disease |
title_short | Stem Cell Treatment for Alzheimer’s Disease |
title_sort | stem cell treatment for alzheimer’s disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227270/ https://www.ncbi.nlm.nih.gov/pubmed/25342318 http://dx.doi.org/10.3390/ijms151019226 |
work_keys_str_mv | AT liming stemcelltreatmentforalzheimersdisease AT guokequan stemcelltreatmentforalzheimersdisease AT ikeharasusumu stemcelltreatmentforalzheimersdisease |