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Stem Cell Treatment for Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neu...

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Detalles Bibliográficos
Autores principales: Li, Ming, Guo, Kequan, Ikehara, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227270/
https://www.ncbi.nlm.nih.gov/pubmed/25342318
http://dx.doi.org/10.3390/ijms151019226
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author Li, Ming
Guo, Kequan
Ikehara, Susumu
author_facet Li, Ming
Guo, Kequan
Ikehara, Susumu
author_sort Li, Ming
collection PubMed
description Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD.
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spelling pubmed-42272702014-11-12 Stem Cell Treatment for Alzheimer’s Disease Li, Ming Guo, Kequan Ikehara, Susumu Int J Mol Sci Review Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD. MDPI 2014-10-23 /pmc/articles/PMC4227270/ /pubmed/25342318 http://dx.doi.org/10.3390/ijms151019226 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Ming
Guo, Kequan
Ikehara, Susumu
Stem Cell Treatment for Alzheimer’s Disease
title Stem Cell Treatment for Alzheimer’s Disease
title_full Stem Cell Treatment for Alzheimer’s Disease
title_fullStr Stem Cell Treatment for Alzheimer’s Disease
title_full_unstemmed Stem Cell Treatment for Alzheimer’s Disease
title_short Stem Cell Treatment for Alzheimer’s Disease
title_sort stem cell treatment for alzheimer’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227270/
https://www.ncbi.nlm.nih.gov/pubmed/25342318
http://dx.doi.org/10.3390/ijms151019226
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