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Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates
Reactive and pharmaceutical-grade heparins were used as biologically compatible reducing and stabilizing agents to photochemically synthesize colloidal gold nanoparticles. Aggregates and anisotropic shapes were obtained photochemically under UV black-light lamp irradiation (λ = 366 nm). Heparin-func...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227271/ https://www.ncbi.nlm.nih.gov/pubmed/25342319 http://dx.doi.org/10.3390/ijms151019239 |
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author | Rodríguez-Torres, Maria del Pilar Díaz-Torres, Luis Armando Romero-Servin, Sergio |
author_facet | Rodríguez-Torres, Maria del Pilar Díaz-Torres, Luis Armando Romero-Servin, Sergio |
author_sort | Rodríguez-Torres, Maria del Pilar |
collection | PubMed |
description | Reactive and pharmaceutical-grade heparins were used as biologically compatible reducing and stabilizing agents to photochemically synthesize colloidal gold nanoparticles. Aggregates and anisotropic shapes were obtained photochemically under UV black-light lamp irradiation (λ = 366 nm). Heparin-functionalized gold nanoparticles were characterized by Scanning Electron Microscopy and UV-Vis spectroscopy. The negatively charged colloids were used for the Surface Enhanced Raman Spectroscopy (SERS) analysis of differently charged analytes (dyes). Measurements of pH were taken to inspect how the acidity of the medium affects the colloid-analyte interaction. SERS spectra were taken by mixing the dyes and the colloidal solutions without further functionalization or addition of any aggregating agent. |
format | Online Article Text |
id | pubmed-4227271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-42272712014-11-12 Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates Rodríguez-Torres, Maria del Pilar Díaz-Torres, Luis Armando Romero-Servin, Sergio Int J Mol Sci Article Reactive and pharmaceutical-grade heparins were used as biologically compatible reducing and stabilizing agents to photochemically synthesize colloidal gold nanoparticles. Aggregates and anisotropic shapes were obtained photochemically under UV black-light lamp irradiation (λ = 366 nm). Heparin-functionalized gold nanoparticles were characterized by Scanning Electron Microscopy and UV-Vis spectroscopy. The negatively charged colloids were used for the Surface Enhanced Raman Spectroscopy (SERS) analysis of differently charged analytes (dyes). Measurements of pH were taken to inspect how the acidity of the medium affects the colloid-analyte interaction. SERS spectra were taken by mixing the dyes and the colloidal solutions without further functionalization or addition of any aggregating agent. MDPI 2014-10-23 /pmc/articles/PMC4227271/ /pubmed/25342319 http://dx.doi.org/10.3390/ijms151019239 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rodríguez-Torres, Maria del Pilar Díaz-Torres, Luis Armando Romero-Servin, Sergio Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title | Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title_full | Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title_fullStr | Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title_full_unstemmed | Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title_short | Heparin Assisted Photochemical Synthesis of Gold Nanoparticles and Their Performance as SERS Substrates |
title_sort | heparin assisted photochemical synthesis of gold nanoparticles and their performance as sers substrates |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227271/ https://www.ncbi.nlm.nih.gov/pubmed/25342319 http://dx.doi.org/10.3390/ijms151019239 |
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