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The role of drug transporters in the kidney: lessons from tenofovir

Tenofovir disoproxil fumarate, the prodrug of nucleotide reverse transcriptase inhibitor tenofovir, shows high efficacy and relatively low toxicity in HIV patients. However, long-term kidney toxicity is now acknowledged as a modest but significant risk for tenofovir-containing regimens, and continuo...

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Detalles Bibliográficos
Autores principales: Moss, Darren M., Neary, Megan, Owen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227492/
https://www.ncbi.nlm.nih.gov/pubmed/25426075
http://dx.doi.org/10.3389/fphar.2014.00248