Cargando…

PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS

Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Epoxyeicosatrienoic acids (EETs) are biologically active metabolites of arachidonic acids capable of activating protective cellular pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Samokhvalov, Victor, Vriend, Jelle, Jamieson, Kristi L., Akhnokh, Maria K., Manne, Rajkumar, Falck, John R., Seubert, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227494/ https://www.ncbi.nlm.nih.gov/pubmed/25426073 http://dx.doi.org/10.3389/fphar.2014.00242

Ejemplares similares

CYP epoxygenase metabolites of docosahexaenoic acid protect HL-1 cardiac cells against LPS-induced cytotoxicity through SIRT1
por: Samokhvalov, V, et al.
Publicado: (2015)

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications
por: Falck, John R., et al.
Publicado: (2014)

11,12-EET Regulates PPAR-γ Expression to Modulate TGF-β-Mediated Macrophage Polarization
por: Li, Xiaoming, et al.
Publicado: (2023)

Correction to 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications
por: Falck, John R., et al.
Publicado: (2014)

Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice
por: Hye Khan, Md. Abdul, et al.
Publicado: (2019)

SIRT Is Required for EDP-Mediated Protective Responses toward Hypoxia–Reoxygenation Injury in Cardiac Cells
por: Samokhvalov, Victor, et al.
Publicado: (2016)

Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury
por: Akhnokh, Maria K., et al.
Publicado: (2016)

The Anti-inflammatory Effect of Soluble Epoxide Hydrolase Inhibitor and 14, 15-EET in Kawasaki Disease Through PPARγ/STAT1 Signaling Pathway
por: Dai, Na, et al.
Publicado: (2020)

Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation
por: Samokhvalov, Victor, et al.
Publicado: (2019)

Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity
por: Imig, John D., et al.
Publicado: (2021)

The Contribution of Arachidonic Acid Metabolites EETs to Inflammation in Obesity
por: Mashayekhi, Mona, et al.
Publicado: (2021)

Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats
por: Walkowska, Agnieszka, et al.
Publicado: (2021)

Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats
por: Neckář, Jan, et al.
Publicado: (2019)

Aging, Estrogen Loss and Epoxyeicosatrienoic Acids (EETs)
por: Lee, Alison R., et al.
Publicado: (2013)

“NETs and EETs, a Whole Web of Mess”
por: Williams, Tyler L., et al.
Publicado: (2020)

EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway
por: Dong, Ruolan, et al.
Publicado: (2017)

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice
por: Singh, Shailendra P., et al.
Publicado: (2016)

Effects of PPARs Agonists on Cardiac Metabolism in Littermate and Cardiomyocyte-Specific PPAR-γ –Knockout (CM-PGKO) Mice
por: Barbieri, Michelangela, et al.
Publicado: (2012)

Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response
por: Samokhvalov, V, et al.
Publicado: (2013)

Sexually Dimorphic Regulation of EET Synthesis and Metabolism: Roles of Estrogen
por: Huang, An, et al.
Publicado: (2018)

Morphine enhances LPS-induced macrophage apoptosis through a PPARγ-dependent mechanism
por: Lin, Mingying, et al.
Publicado: (2021)

2nd International Conference on Education and Educational Technology (EET 2011)
por: Wang, Yuanzhi
Publicado: (2012)

2nd International Conference on Education and Educational Technology (EET 2011)
por: Wang, Yuanzhi
Publicado: (2012)

20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
por: Eid, Stephanie, et al.
Publicado: (2013)

Theoretical model for neurovascular coupling via interactions of NO, EET, and 20-HETE
por: Kang, Hyuk, et al.
Publicado: (2013)

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2017)

Asperosaponin VI inhibits LPS-induced inflammatory response by activating PPAR-γ pathway in primary microglia
por: Zhang, Jinqiang, et al.
Publicado: (2020)

Sex differences in blood pressure control in SHR: lack of a role for EETs
por: Moulana, Mohadetheh, et al.
Publicado: (2014)

Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes
por: Aliwarga, Theresa, et al.
Publicado: (2018)

LncRNA ACART protects cardiomyocytes from apoptosis by activating PPAR‐γ/Bcl‐2 pathway
por: Wu, Hao, et al.
Publicado: (2019)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

Correction: 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2018)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

Lipodystrophy, Diabetes and Normal Serum Insulin in PPARγ-Deficient Neonatal Mice
por: O’Donnell, Peter E., et al.
Publicado: (2016)

Altered expression of PPAR-γ and TRPC in neonatal rats with persistent pulmonary hypertension
por: Du, Yanna, et al.
Publicado: (2017)

Nebulized PPARγ Agonists: A Novel Approach to Augment Neonatal Lung Maturation and Injury Repair
por: Morales, Edith, et al.
Publicado: (2014)

Dulaglutide Alleviates LPS-Induced Injury in Cardiomyocytes
por: Wang, Rijun, et al.
Publicado: (2021)

Association of the PPAR-γ Gene with Altered Glucose Levels and Psychosis Profile in Schizophrenia Patients Exposed to Antipsychotics
por: Liu, Yun-Ru, et al.
Publicado: (2014)

PPARγ and Apoptosis in Cancer
por: Elrod, Heath A., et al.
Publicado: (2008)

PPARγ, neuroinflammation, and disease
por: Mrak, Robert E, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_vqfe8tfsa1seqsocvho1tjh227