Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.

[Image: see text] Salvadenosine, (1) a rare 5′-deoxy-5′-(methylthio) nucleoside, was isolated from the deep-water Bahaman tunicate Didemnum sp. The structure was solved by integrated analysis of MS and 1D and 2D NMR data. We revise the structure of the known natural product, hamiguanosinol, which is...

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Autores principales: Jamison, Matthew T., Boddy, Christopher N., Molinski, Tadeusz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227578/
https://www.ncbi.nlm.nih.gov/pubmed/25284474
http://dx.doi.org/10.1021/jo501486p
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author Jamison, Matthew T.
Boddy, Christopher N.
Molinski, Tadeusz F.
author_facet Jamison, Matthew T.
Boddy, Christopher N.
Molinski, Tadeusz F.
author_sort Jamison, Matthew T.
collection PubMed
description [Image: see text] Salvadenosine, (1) a rare 5′-deoxy-5′-(methylthio) nucleoside, was isolated from the deep-water Bahaman tunicate Didemnum sp. The structure was solved by integrated analysis of MS and 1D and 2D NMR data. We revise the structure of the known natural product, hamiguanosinol, which is a constitutional isomer of 1, to 5 by interpretation of the spectroscopic data and comparison with synthesized nucleosides.
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spelling pubmed-42275782015-10-03 Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp. Jamison, Matthew T. Boddy, Christopher N. Molinski, Tadeusz F. J Org Chem [Image: see text] Salvadenosine, (1) a rare 5′-deoxy-5′-(methylthio) nucleoside, was isolated from the deep-water Bahaman tunicate Didemnum sp. The structure was solved by integrated analysis of MS and 1D and 2D NMR data. We revise the structure of the known natural product, hamiguanosinol, which is a constitutional isomer of 1, to 5 by interpretation of the spectroscopic data and comparison with synthesized nucleosides. American Chemical Society 2014-10-03 2014-11-07 /pmc/articles/PMC4227578/ /pubmed/25284474 http://dx.doi.org/10.1021/jo501486p Text en Copyright © 2014 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Jamison, Matthew T.
Boddy, Christopher N.
Molinski, Tadeusz F.
Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title_full Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title_fullStr Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title_full_unstemmed Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title_short Salvadenosine, a 5′-Deoxy-5′-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
title_sort salvadenosine, a 5′-deoxy-5′-(methylthio) nucleoside from the bahamian tunicate didemnum sp.
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227578/
https://www.ncbi.nlm.nih.gov/pubmed/25284474
http://dx.doi.org/10.1021/jo501486p
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