Cargando…
Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2
The role of glia in modulating neuronal network activity is an important question. Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane proteoglycan nerve-glia antigen 2 (NG2) and are unique glial cells receiving synaptic input from neurons. The development of NG2+ OPC...
Autores principales: | Sakry, Dominik, Neitz, Angela, Singh, Jeet, Frischknecht, Renato, Marongiu, Daniele, Binamé, Fabien, Perera, Sumudhu S., Endres, Kristina, Lutz, Beat, Radyushkin, Konstantin, Trotter, Jacqueline, Mittmann, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227637/ https://www.ncbi.nlm.nih.gov/pubmed/25387269 http://dx.doi.org/10.1371/journal.pbio.1001993 |
Ejemplares similares
-
The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2
por: Maus, Frank, et al.
Publicado: (2015) -
The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling
por: Nayak, Tanmoyita, et al.
Publicado: (2018) -
Oligodendrocyte Precursor Cells Synthesize Neuromodulatory Factors
por: Sakry, Dominik, et al.
Publicado: (2015) -
PTEN negatively regulates the cell lineage progression from NG2(+) glial progenitor to oligodendrocyte via mTOR-independent signaling
por: González-Fernández, Estibaliz, et al.
Publicado: (2018) -
Alexander Disease Mutations Produce Cells with Coexpression of Glial Fibrillary Acidic Protein and NG2 in Neurosphere Cultures and Inhibit Differentiation into Mature Oligodendrocytes
por: Gómez-Pinedo, Ulises, et al.
Publicado: (2017)