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A Three-Dimensional Computational Model of Collagen Network Mechanics

Extracellular matrix (ECM) strongly influences cellular behaviors, including cell proliferation, adhesion, and particularly migration. In cancer, the rigidity of the stromal collagen environment is thought to control tumor aggressiveness, and collagen alignment has been linked to tumor cell invasion...

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Detalles Bibliográficos
Autores principales: Lee, Byoungkoo, Zhou, Xin, Riching, Kristin, Eliceiri, Kevin W., Keely, Patricia J., Guelcher, Scott A., Weaver, Alissa M., Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227658/
https://www.ncbi.nlm.nih.gov/pubmed/25386649
http://dx.doi.org/10.1371/journal.pone.0111896