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Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers

The transcription activator–like effectors (TALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat (CRISPR) associated protein (Cas9) utlilize distinct molecular mechanisms in targeting site recognition. The two proteins can be modified to carry additional functional doma...

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Detalles Bibliográficos
Autores principales:	Gao, Xuefei, Tsang, Jason C.H., Gaba, Fortis, Wu, Donghai, Lu, Liming, Liu, Pentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227760/ https://www.ncbi.nlm.nih.gov/pubmed/25223790 http://dx.doi.org/10.1093/nar/gku836

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