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Rad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiae

DNA damage response and repair proteins are centrally involved in genome maintenance pathways. Yet, little is known about their functional role under non-DNA damage-inducing conditions. Here we show that Rad9 checkpoint protein, known to mediate the damage signal from upstream to downstream essentia...

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Detalles Bibliográficos
Autores principales: Andreadis, Christos, Nikolaou, Christoforos, Fragiadakis, George S., Tsiliki, Georgia, Alexandraki, Despina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227768/
https://www.ncbi.nlm.nih.gov/pubmed/25300486
http://dx.doi.org/10.1093/nar/gku915