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Defective histone supply causes condensin-dependent chromatin alterations, SAC activation and chromosome decatenation impairment
The structural organization of chromosomes is essential for their correct function and dynamics during the cell cycle. The assembly of DNA into chromatin provides the substrate for topoisomerases and condensins, which introduce the different levels of superhelical torsion required for DNA metabolism...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227775/ https://www.ncbi.nlm.nih.gov/pubmed/25300489 http://dx.doi.org/10.1093/nar/gku927 |