Chemical probing of RNA with the hydroxyl radical at single-atom resolution

While hydroxyl radical cleavage is widely used to map RNA tertiary structure, lack of mechanistic understanding of strand break formation limits the degree of structural insight that can be obtained from this experiment. Here, we determine how individual ribose hydrogens of sarcin/ricin loop RNA par...

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Detalles Bibliográficos
Autores principales: Ingle, Shakti, Azad, Robert N., Jain, Swapan S., Tullius, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227780/
https://www.ncbi.nlm.nih.gov/pubmed/25313156
http://dx.doi.org/10.1093/nar/gku934

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