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hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling
The increased cap-independent translation of anti-apoptotic proteins is involved in the development of drug resistance in lung cancer but signalling events regulating this are poorly understood. Fibroblast growth factor 2 (FGF-2) signalling-induced S6 kinase 2 (S6K2) activation is necessary, but the...
Autores principales: | Roy, Rajat, Durie, Danielle, Li, Hui, Liu, Bing-Qian, Skehel, John Mark, Mauri, Francesco, Cuorvo, Lucia Veronica, Barbareschi, Mattia, Guo, Lin, Holcik, Martin, Seckl, Michael J., Pardo, Olivier E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227786/ https://www.ncbi.nlm.nih.gov/pubmed/25324306 http://dx.doi.org/10.1093/nar/gku953 |
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