Cargando…

Global identification of target recognition and cleavage by the Microprocessor in human ES cells

The Microprocessor plays an essential role in canonical miRNA biogenesis by facilitating cleavage of stem-loop structures in primary transcripts to yield pre-miRNAs. Although miRNA biogenesis has been extensively studied through biochemical and molecular genetic approaches, it has yet to be addresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Seong, Youngmo, Lim, Do-Hwan, Kim, Augustine, Seo, Jae Hong, Lee, Young Sik, Song, Hoseok, Kwon, Young-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227787/
https://www.ncbi.nlm.nih.gov/pubmed/25326327
http://dx.doi.org/10.1093/nar/gku957

Ejemplares similares