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TRAP150 activates splicing in composite terminal exons

The spliceosomal factor TRAP150 is essential for pre-mRNA splicing in vivo and, when overexpressed, it enhances splicing efficiency. In this study, we found that TRAP150 interacted with the cleavage and polyadenylation specificity factor (CPSF) and co-fractionated with CPSF and RNA polymerase II. Mo...

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Detalles Bibliográficos
Autores principales:	Lee, Kuo-Ming, Tarn, Woan-Yuh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227790/ https://www.ncbi.nlm.nih.gov/pubmed/25326322 http://dx.doi.org/10.1093/nar/gku963

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